New Experimental Cancer Treatment Regimen

To appear in Medical Hypotheses & Research Journal

 

 

Dr. Payne’s latest paper to clear peer-review is titled “Effecting Oncolysis by Depleting Intracellular Glutathione, Boosting Oxidative Stress, and Reducing IGF-I”. This experimental cancer treatment approach is designed for use to complement standard oncolytic approaches or as a stand alone “heroic measure”.

 

Dr. Payne’s paper will appear in the upcoming issue of “Medical Hypotheses and Research” (The Journal for Innovative Ideas in Biomedical Research, http://www.journal-mhr.com/). An abstract plus keyword list follows below.

 

Readers interested in obtaining further information or a reprint should contact Dr. Payne at DrAGPayne@yahoo.com 

Abstract

            The regimen contained in this paper exploits critical pathways in the life-sustaining biology of many tumor cell types in such a way as to make oncolysis more probable. This approach includes dietary methionine restriction and other means to lower intracellular glutathione with the specific goal of compromising intracellular oxidative defenses; iron loading and liberation of ferritin iron followed by measures geared to generate cell lethal free radicals cascades; and dietary and oral agent intervention oriented to reduce tumor cell-modulating IGF-I levels.            

Key Words

ATP; cancer; cobalt phthalocyanines; experimental cancer treatment; ferritin-mediated intracellular hyperthermia; gamma radiation; hyperthermia; Insulin Growth Factor-I (IGF-I); insulin; iron phthalocyanines; low methionine diet; oncolysis; oncolytic; solid

tumors; thyroid hormone